Objective:To explore the influential factors of undergoing total thyroidectomy in differentiated thyroid carcinoma. Methods: The data of laryngeal recurrent nerve injury and hypoparathyroidism in 72 patients with differentiated thyroid carcinoma after total thyroidectomy from 2002 to 2010, were retrospectively studied. Results: The hypoparathyroidism were significantly related to the times of thyroid operation, lymph nodes metastases of central compartment and the extraglandular invasion of primary tumor ( P ＜ 0.05 ), and irrelative to the dissection of neck lymph nodes. The laryngeal recurrent nerve injury was irrelative to those factors( P ＞ 0.05 ). Conclusion: The influential factors of total thyroidectomy in differentiated thyroid carcinoma includes the times of thyroid operation, the lymph nodes metastases of central compartment and the extraglandular invasion of primary tumor.%目的:探讨甲状腺全切除术治疗分化型甲状腺癌安全性的相关因素.方法:回顾性分析本院2002年1月至2010年1月期间72例甲状腺全切术治疗分化型甲状腺癌的病历资料,分析甲状旁腺功能减退和喉返神经损伤的发生情况.结果:甲状旁腺功能减退发生与再次手术、原发肿瘤腺体外侵犯、中央区淋巴结转移有关,与是否行颈清无关;喉返神经的损伤与上述因素无关.结论:影响甲状腺全切术治疗分化型甲状腺癌安全性的相关因素有:手术次数、原发肿瘤腺体外侵犯和中央区淋巴结转移.
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