连续性血液滤过联合血液灌流治疗危重症并急性肾衰竭

摘要

目的：对危重症合并急性肾衰竭患者采用连续性血液滤过联合血液灌流治疗，观察和分析其治疗效果。方法：将116例病例按照住院先后顺序分为对照组和治疗组。对照组采用常规方法治疗，治疗组在对照组治疗基础上采用连续性血液滤过联合血液灌流治疗。结果：2组患者治疗前APACHEⅡ评分比较无显著性差异（P＞0.05）；治疗后，24 h、48 h、72 h的APACHEⅡ评分均下降，与治疗前比较有显著性差异（P＜0.05），治疗组优于对照组（P＜0.05）。治疗后2组血清BUN和Scr、TBIL等均明显下降，且治疗组优于对照组；治疗组死亡率为3.45％，明显低于对照组的13.79％（ P＜0.05）。结论：采用连续性血液滤过联合血液灌流治疗危重症合并急性肾衰竭患者，可清除细胞因子，降低死亡率。%Objective:To observe the effect of continuous hemofiltration combined with blood perfusion in treatment of critical patients with acute renal failure.Methods:116 patients were divided into control group and treatment group.Control group:only had basis conventional treatment.Treatment group:had continuous hemofiltration combined with blood perfusion therapy in addition to basis.Results:APACHEⅡ score had no difference before treatment in both groups ( P >0.05 );After treatment,24 h,48 h,72 h APACHEⅡscore were decreased, compared with before treatment( P<0.05) in both groups;But the treatment group was better than that of control group( P<0.05).In both groups the serum BUN and Scr,TBIL were significantly decreased after treatment,but in the treatment group was better than in the control group;3.45%mortality in treatment group was obviouslylower than 13.79% in the control group ( P <0.05 ).Conclusion:Continuous hemofiltration combined with blood perfusion for critical patients with acute renal failure can clear cytokines, reduce mortality.