地佐辛复合依托咪酯用于老年人膀胱镜检查的临床研究

摘要

目的：探讨依托咪酯复合地佐辛静脉麻醉用于膀胱镜检查术的效果和安全性。方法：将60例需进行膀胱镜检术的老年患者随机分为2组：采用依托咪酯复合地佐辛静脉麻醉为观察组（A组）；采用芬太尼复合丙泊酚静脉麻醉为对照组（B组）。比较两组患者术中心率、主动脉平均压力（MAP）、呼吸、SpO2的变化，术中镇痛效果、苏醒时间及术后恶心呕吐、头晕等并发症。结果：B组术中MAP和HR明显低于A组（P＜0．05），其他时间点2组无统计学差异（P＞0．05）。呼吸抑制发生率A组明显低于B组（P＜0．05）。苏醒时间A组短于B组，但无统计学意义。结论：地佐辛复合依托咪酯用于老年人膀胱镜检查术，麻醉效果满意，血流动力学平稳，不良反应少，是此种手术安全、可靠的麻醉方法之一。%Objective :To investigate the effect and feasibility of pentazocine compound etomidate anesthesia in the eld-erly application painless cystoscopy .Methods :60 elderly cases of cystoscopy were divided into two groups randomly . Group A is general anesthesia with pentazocine compound etomidate (30 cases) and group B has propofol compound fentanyl (30 cases) .Compare the variation of HR ,MAP ,RR ,SpO2 ,the effect of analgesia ,respiratory depression ,post-operative nausea and vomiting and other complications of anesthesia .Results:Different levels of blood pressure dropped after anesthesia of both groups and group B is more significancely .While there is no statistical difference in the 2 groups at other time(P>0 .05) .Propotion of respiratoy depression of group A is less than group B (P<0 .05) .The wa-king time of group A is less than group B but there is no difference in the 2 groups .Conclusion:Pentazocine compound etomidate anesthesia in the elderly eapplication painless cystoscopy ,satisfied with the anesthetic effect ,it is a safe and reliable method of anesthesia for such surgery .