出生缺陷二级预防策略的研究

摘要

Objective:To evaluate and compare the economic effectiveness of three strategies of the sec-ondary prevention for birth defects in order to provide the basis for the prevention decision on congenital disa-bilities .Methods:A decision tree model was used to make a decision analysis on the cost-effectiveness of the three strategies .Results :The birth defects detection rates of three strategies were 82 .82% ,98 .2% ,94 . 50% respectively .The cost of one birth defect detected of the third strategy was lowest .Conclusions :In-creasing an ultrasound screening for high-risk pregnant women is an economical and effective strategy to pre-vent birth defects .%目的：评价、比较出生缺陷的3种二级预防策略的经济学效果，为有效预防先天性残疾提供决策依据。方法：采用决策树模型，对3种策略的成本-效果进行比较。结果：3种策略的出生缺陷检出率分别为82．82％、98．2％、94．50％，策略3成本/效果比最低。结论：高危孕妇增加超声筛查是一种既经济又有效的预防策略。