18F-FDG PET-CT与磁共振成像在评估淋巴瘤骨髓浸润中的价值

摘要

淋巴瘤是血液系统常见的恶性肿瘤之一,淋巴瘤是否有骨髓浸润在淋巴瘤的诊断、分期、尤其化疗早期疗效评估方面具有重要的价值.目前临床上仍主要依据骨髓穿刺活组织检查诊断淋巴瘤骨髓浸润,但常因取材的局限性出现假阴性,延误治疗.近年影像技术日益发展、完善,为淋巴瘤骨髓浸润提供了新的检测手段,提高了诊断的敏感性和特异性.文章对磁共振成像(MRI)、18F-FDG PET-CT这两种新的影像检查方法在淋巴瘤骨髓浸润方面的研究作一综述.%As one of the most common hematologic malignancy,bone marrow involvement in lymphoma has diagnosis and therapeutic implications,especially in early chemotherapy curative effect evaluation.At present,the diagnosis of bone marrow involvement was mainly depend on bone marrow biopsy,but it has poor sensitivity suffered from sampling errors resulting in delayed treatment.Recently,with the development and perfect of imaging technology,the new means of detection with higher sensitivity and specificity are applied to diagnosis of bone marrow involvement.In this article,the application of imaging,magnetic resonance imaging (MRI) and 18F-FDG PET-CT in this area is reviewed.