功能性消化不良患者胃中间横带面积百分比与胃排空的关系

摘要

目的 探讨功能性消化不良(FD)患者胃中间横带(MTB)面积百分比与胃排空的关系.方法 48例受检者分为正常对照组、FD组和大剂量组,进行核素胃排空检查,采用感兴趣区技术获得全胃及分胄区时间-放射性计数比曲线,由曲线可知全胃半排时间(GET1/2)及不同测试点全胃、分胃区面积,计算不同胃区与个胃面积百分比.对GET1/2和MTB面积百分比分别行单因素统计分析、相关性分析.结果 FD组、大剂量组GET 1/2明显增加,与对照组比较,差异有显著性(P<0.05,P<0.01).但前两组之间差异无显著性(P>0.05);与对照组比较,各时相FD组MTB面积比显著性均增加(P<0.05),大剂量组差异无显著性(P>0.05);各时相MTB区而积百分比与GET1/2有相关性(P<0.05).结论 FD患者MTB面积百分比增加、GET1/2延长,MTB起到"闸门"的作用,对胃内食物分布及排空进行调节.%Objective To investigate the relationship between the percentage of midgastric trans- verse band (MTB) area and the time of gastric emptying in patients with functional dyspep- sia (FD). Methods 48 subjects were divided into healthy subjects,FD and big dosage groups, and underwent gastric emptying imaging with single photon emission computed tomograph. The time of the whole and different gastric areas was obtained by region of interest technique and the activity curve was drawn automatically or artificially,the half gastric emptying time (GET1/2) of the whole stomach and the areas of the whole and subregion stomach were obtained from the curve,and the percentage of the whole and different gastric areas was calculated. Results GET1/2 in FD group and big dosage group increased obviously and there was a significant dif- ference when compared with healthy subjects (P <0.05 or P<0.01),but there was no significant difference between the two groups (P>0.05). The percentage of MTB area in FD group increased obviously and there was a significant difference when compared with healthy subjects (P<0.05), but thcre was no significant difference between big dosage group and healthy subjects (P>0.05). The percentage of MTB area was correlated with GET1/2 at different time (P<0.05). Conclu- sion Both the percentage of MTB area and GET1/2 are increased in patients with FD. MTB plays a role as sluice gate in regulating food distribution and empting of the stomach.