马来酸二甲酯催化合成新工艺研究

摘要

The article studies using p-toluene sulfonic acid as the catalyst of the esterfication of methanol and maleic anydride .The study focused on the reaction temperature amount of the catalyst the ratio of methanol to maleic anhydride and reaction time .The experimental results indicate the increase of reaction temperature benefits the production of dimethyl maleate with the optimum range being 105℃-125℃.Similarly increase of catalyst amount the ratio of methanol to maleic nhydride and reaction time also help the production of the goal ester .With the amount of the catalyst being at 15 percent of the maleic anhydride the ratio of the methanol to maleic anhydride being 2 .5∶1 and reacting 90 min the yield of dimmethyl maleate may be 99 .2%.%研究了用固体酸催化剂对甲苯磺酸催化马来酸酐与甲醇酯化反应合成马来酸二甲酯的新工艺合成条件。酯化反应分别考察了反应的温度、催化剂用量、醇酐比和反应时间等条件对马来酸二甲酯收率的影响。研究结果表明，温度升高有利于马来酸二甲酯的生成，最佳反应温度为105℃-125℃。适当增加催化剂用量，提高醇酐摩尔配比，延长反应时间均有利于顺丁烯二酸二甲酯的生成，在催化剂用量15％（与顺酐的质量百分比），醇酐摩尔比为2．5∶1，反应时间90分钟时，二酯的得率为99．2％。