Objective:To analyze the prevalence of syphilis infection and influence factors of syphilis infection among the male STD attendants in Songyuan City of Jilin Province, and to provide theoretical basis for the development and implementation of syphilis intervention policy.Methods:A questionnaire survey and serological tests were conducted among the men who went to STD clinic for treatment in the ZhanDong Dermatology Specialist Hospital or Qianguo County Hospital in Songyuan City from 2011 to 2015.Chi-square test was performed to compare the prevalences of syphilis infection between different groups.Multivariable Logistic regression model was used to find the independent factors of syphilis infection among the male STD attendants.Results:Of all 2 000 male STD attendants who involved in the study,the mean age was (34.50±9.03)years old.218 persons (10.90%)of them had sexual behavior with female sex workers in the last three months,433 persons (21.65%)of them had temporary sexual behavior in the last three months,42 persons (2.10%)of them had homosexual behavior in the last three months.Of the respondents,238 persons (11.90%)had a previous diagnosis of sexually transmitted diseases,86 persons of them had gonorrhea (36.13%),43 persons had syphilis (18.07%),15 persons had genital tract Chlamydia (6.30%),55 persons had genital herpes (23.11%),40 persons had genital herpes (16.81%),and 1 person had combined infection of gonorrhea and syphilis. The prevalence of syphilis of 2 000 male STD attendants was 6.4%.From 2011 to 2015,there was a decrease in the prevalences of syphilis (χ2 =44.25,P <0.001).In the last 3 months, the risk of the male STD attendants who had commercial sex with prostitute,temporary sex behavior,homosexual behavior and a history of STD infection to be infected with syphilis in the past were 3.75 times (OR= 3.75,95% CI:2.46 - 5.71),2.31 times (OR = 2.31,95% CI: 1.56 - 3.41),2.97 times (OR=2.97,95%CI:1.33-6.64)and 1.69 times (OR=1.69,95%CI:1.07-2.67)than those who did not have those behaviors,respectively. Conclusion:There is a significantly decreasing tendency in the prevalence of syphilis among the male STD attendants in Songyuan City in the past 5 years.The high risk sexual behaviors are the main influence factors of syphilis infection among them.%目的：分析吉林省松原市性病门诊男性就诊人群梅毒感染现状及梅毒感染的影响因素，为梅毒干预政策的制定和实施提供理论依据。方法：选取2011—2015年吉林省松原市占东皮肤科专科医院和前郭县医院性病门诊就诊的男性就诊者进行问卷调查和血清学检测，对计数资料采用率和构成比进行描述性分析。不同特征人群之间梅毒感染率比较采用χ2检验。采用 Logistic 多因素回归模型筛选可能影响性病门诊男性就诊者梅毒感染率的独立影响因素。结果：本研究共调查性病门诊男性就诊者2000人，平均年龄（34.50±9.03）岁，其中218人（10.90％）最近3个月与暗娼发生过性行为，433人（21.65％）最近3个月与临时性伴发生过性行为，42人（2.10％）曾与同性发生过肛交性行为。调查对象中，238例（11.90％）既往诊断患有性病，其中86例（36.13％）曾患有淋病，43例（18.07％）患有梅毒，15例（6.30％）有生殖道沙眼衣原体感染，55例（23.11％）患有尖锐湿疣，40例（16.81％）患有生殖器疱疹，1例淋病与梅毒合并感染。性病门诊男性就诊者2000人中血清梅毒抗体阳性率为6.4％，2011—2015年梅毒抗体阳性率呈逐年下降趋势（χ2＝44.25，P ＜0.001）。近3个月存在商业性行为、临时性行为、同性性行为及有性病既往史的性病门诊男性就诊者梅毒感染的危险度分别是不具有该行为者的3.75倍（OR＝3.75，95％CI：2.46～5.71）、2.31倍（OR＝2.31，95％CI：1.56～3.41）、2.97倍（OR＝2.97，95％ CI：1.33～6.64）和1.69倍（OR＝1.69，95％ CI：1.07～2.67）。结论：吉林省松原市近5年性病门诊男性就诊者梅毒患病率呈下降趋势，高危性行为是其感染梅毒的主要影响因素。
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