川崎病并发冠状动脉病变诊断及发病机制的研究进展

摘要

Kawasaki disease( KD) is an acute systemic small vasculitis syndrome,mainly involving coronary artery,which can cause dilatation of coronary artery,coronary artery aneurysm,coronary artery stenosis,coronary artery occlusion and myocardial infarction. KD is the main reason for acquired heart disease in children. So it is research on diagnosis and pathogenesis of KD that play a positive role in the prevention and treatment of KD with coronary artery lesions. This paper review the diagnosis and pathogenesis of Kawasaki Disease with coronary artery lesions.%川崎病是一种急性全身中小血管炎性综合征，主要累及冠状动脉，可引起冠状动脉扩张、冠状动脉瘤、冠状动脉狭窄与闭塞性病变，甚至可导致心肌梗死，是儿童后天获得性心脏病的主要原因之一。因此研究KD并发冠状动脉病变的发病机制对预防及治疗KD心血管系统并发症有积极作用。本文综述近年来对KD并发冠状动脉病变诊断及发病机制的研究进展。