鼻咽癌形态学发生发展的体视学定量研究

摘要

AIM　To study the morphological changing law of devel epment of nasopharyngeal carcinoma. METHODS　Quantity sterological parameters of E R & Go and TMF & TF of different periodical nasopharyngeal epithelia cells were measured analysed and calculated by sterological and statistical method. RESULTS　Parameters w ere different statistically among different periodical nasopharyngeal epithelia cells. CONCLUSION　During the canceyation courses of nasopharyngeal epithelia, epithelia squamous maturial tredency becomes streng ther and columnar maturial tredency becomes weeker, which has pathological significance.%目的探讨鼻咽癌发生发展过程中形态学变化规律. 方法应用体视学技术测算鼻咽癌发生发展过程中不同时期鼻咽上皮细胞胞质泡状系统（ER & GO）和张力原纤维/微丝（TMF & TF）的数量，并进行统计学比较. 结果胞质泡状系统和张力原纤维/微丝的数量在不同鼻咽上皮细胞中数量不同，在统计学有显著性差异. 结论鼻咽上皮在逐渐癌变过程中，向鳞状上皮分化的趋势加强，而向柱状上皮分化的趋势减弱，这一形态改变具有病理学意义.