藻蓝蛋白是一种存在于蓝藻、螺旋藻细胞中的色素蛋白复合体,除了能够捕获光能为藻类细胞提供能量外,藻蓝蛋白还具有抗炎性、抗肿瘤、抗氧化等多种生理功能,全面了解和掌握藻蓝蛋白的生理调控功能以及作用机制对藻蓝蛋白的开发与利用有着重要的指导意义.作者以藻蓝蛋白的研究现状出发,分别从抗肿瘤、抗炎、抗氧化以及免疫调节活性几个方面对藻蓝蛋白的生理功能和作用机制进行了阐述,对藻蓝蛋白提取过程中关键瓶颈——藻毒素的去除方法进行了总结和分析,并进一步提出了研究藻蓝蛋白调控机制的新筛选方法.作者为深入研究藻蓝蛋白的调控机理以及进一步开发安全性药物提供参考.%Phycocyanin is a kind of light-harvesting compound existed in Spirulina.In addition to providing energy for the survival of algae cells by capturing light,phycocyanin possesses many physiological functions such as anti-tumor,anti-inflammatory and antioxidant.Fully understanding the physiological function and regulation mechanism of phycocyanin has important guiding significance to its development and utilization.This paper reviews the anti-tumor,anti-inflammatory,antioxidant and immunoregulatory activity functions ofphycocyanin,analyzes the removal method of the key bottlenecks in the process of phycocyanin extracfion-microcystin,and also puts forward a novel method of studying phycocyanin regulation mechanism.This present paper provides references for further investigation into regulation mechanisms of phycocyanin and development of safety drugs.
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