益气养阴活血中药对舒张性心力衰竭患者ET-1和ANGⅡ的影响

摘要

目的 观察益气养阴活血中药对舒张性心力衰竭患者内皮素-1(ET-1)和血管紧张素Ⅱ(ANGⅡ)的影响.方法 将160例舒张性心力衰竭患者随机分为两组,均予以西药常规治疗,治疗组在此基础上加用中药汤剂口服.检测两组治疗前后血清ET-1和ANGⅡ水平.结果 治疗组ET-1和ANGⅡ表达水平较对照组显著降低.结论 益气养阴活血中药能降低舒张性心力衰竭患者ET-1和ANGⅡ的表达水平.%Objective: To examine the influence of Yiqiyangyinhuoxue Decoction on endothelin-1 (ET-1) and angiotensin II (ANG II )in patients with diastolic heart failure(DHF). Methods: 160 patients with DHF were randomly divided into the control group and the treatment group (80 patients). The control group were treated with routine western medicine. The treatment group were treated with decoction besides the control group therapy. Results: The ET-1 and ANG II of the treatment group were decreased more obviously than those of the control group. The effect of the treatment group was superior to that of the control group. Conclusion: Expressions including ET-1 and ANG II are lowered remarkably when used the Yiqiyangyinhuoxue decoction.