经尿道2μm激光前列腺剜除术治疗良性前列腺增生的3年随访观察

摘要

Objective To investigate the safety and efficiency of transurethral 2μm laser enu-cleation in treating the benign prostatic hyperplasia(BPH). Methods 190 cases of BPH were di-vided into two groups randomly.They were underwent transurethral prostate enucleation with 2μm laser in our hospital from April 2009 to March 2011.The pre,mid,and postoperative clinical inde-xes were collected and analyzed. Results The amount of removed prostatic tissue was (23.96± 15.8)g.The average operational duration was (70.5±11.6)min.The mean blood loss during opera-tion was (20.2±16.9)ml.There were no significant change in serum sodium concentration and he-moglobin levels before comand after surgery.The international prostate symptoms score (IPSS), quality of life (QOL)and maximal urinary flow rate (Qmax)was improved significantly after opera-tion.3 patients developed into the secondary urinary incontinence and then recovered in 3 months lat-er through functional exercises. Conclusions The transurethral prostate enucleation with 2μm la-ser in treating the BPH has more radical resection of hyperplastic prostate tissue,less blood loss. The transurethral prostate enucleation with 2 μm laser is a safe and effective minimally invasive treatment for BPH,and showing the stable and sustained curative effects.%目的：探讨经尿道2μm激光前列腺剜除术治疗BP H的疗效和安全性。方法比较分析2009年4月至2011年3月接受经尿道2μm激光前列腺剜除术治疗的190例 BPH患者术前、术中及术后相关临床指标,随访时间长达3年。结果手术平均切除前列腺组织(23.96±15.8)g,平均手术时间(70.5±11.6)min,术中平均出血量(20.2±16.9)ml。所有患者手术前后血钠浓度及血红蛋白水平均无明显变化,国际前列腺症状评分、生活质量评分及最大尿流率均较术前有明显改善。3例患者术后出现继发性尿失禁,经功能锻炼3个月后康复。结论经尿道2μm 激光前列腺剜除术具有良好的止血效果,切除增生前列腺组织更彻底,手术风险显著降低,是治疗 BP H 安全、有效的微创手术方式,疗效持久、稳定。