组织学前列腺炎对前列腺增生临床进展的影响因素分析

摘要

[目的]探讨组织学前列腺炎对良性前列腺增生(BPH)临床进展的影响.[方法]对手术治疗的143例BPH患者的临床资料进行回顾性分析,根据术后病理学检查前列腺炎的发生情况,分为单纯BPH组(n=35)和伴前列腺炎的BPH组(n=108),对比两组患者的发病年龄,前列腺体积,尿潴留发生率,国际前列腺症状评分(IPSS),最大尿流率 (MFR)和血清前列腺特异抗原(PSA)的数值.[结果]在所选前列腺标本中,75.6%(108/143)的标本同时合并组织学前列腺炎.伴组织学前列腺炎的BPH组患者与单纯BPH组相比其发病年龄、前列腺体积及血清PSA值明显升高(P<0.05),而且其急性尿潴留的发生率要大于单纯BPH组(P<0.05).[结论]BPH患者组织学前列腺炎的检出率较高,组织学前列腺炎明显影响BPH的临床进展,其可能为BPH的致病因素之一.%[Objective] To explore the effect of histological prostatitis on the development of benign prostatic hyperplasia(BPH). [Methods] The clinical data of 143 BPH patients treated by surgery were analyzed retrospectively. According to the incidence of prostatitis by postoperative pathological examination, all patients were divided into simple BPH group( n=35) and BPH with prostatitis group( n=108). The onset age, prostate volume, urlnary retention rate, IPSS, maximum flow rate(MFR) and serum prostate specific antigen(PSA) were compared between two groups. [Results] BPH combined with histological prostatitis occupied 75.6 ％ (108/143) of all prostate specimens. Compared with simple BPH group, the onset age, prostate volume and serum PSA in BPH with histological prostatitis group obviously increased( P ＜0.05). Moreover, the incidence of acute urinary retention in BPH with histological prostates was higher than that in simple BPH group( P ＜0.05). [Conclusion] The detection rate of histological prostatitis in BPH patients is higher. Histological prostatitis has obvious effect on the clinical development of BPH, which may be one of the factors for the pathogenesis of BPH.