肺性脑病与动脉血气参数关系的临床研究

摘要

Objective To discuss the relationship between the occurrence and severity of pulmonary encephalopathy and the a-nalysis of arterial blood gas. Methods 110 patients with chronic cor pulmonale complicated with type 2 respiratory failure were selected to analyze their arterial blood gas and 53 cases of them had pulmonary encephalopathy. The 53 patients were divided into different classes according to the severity of conscious disturbance. Results The incidence of pulmonary encephalopathy increased significantly to 92. 85% when the content of PaCO2 was more than 80 mmHg and PaO2 was less than 50 mmHg. The incidence rose up to 100% when the content of PaCO2 was more than 80 mmHg and the value of pH was less than 7.2. The severity of conscious disturbance was correlated with the content of PaCO2 and PaO2 and PH value. Conclusion Dynamic observation of arterial blood gas can be helpful in the early prevention and prognosis of patients with pulmonary encephalopathy.%目的 研究肺性脑病的发生及临床症状的严重程度与动脉血气参数的关系.方法 研究110例慢性肺源性心脏病并2型呼吸衰竭患者和其中53例发生有肺性脑病患者的血气参数及53例肺性脑病患者中按意识障碍严重程度分组的血气参数.结果 动脉血PaCO2>80 mmHg同时PaO2<50 mmHg,肺性脑病的发生率明显增高(92.85%),动脉血PaCO2>80 mmHg同时pH<7.2,肺性脑病的发生率为100%.患者血气的PaCO2上升及pH、PaO2下降速度越快,患者的意识障碍程度越重.结论 动态观察血气分析参数有助于防治肺性脑病和改善其临床预后.