Objectives To conduct nutritional risk assessment analysis of hand-foot-mouth disease in children and to explore rational and feasible nutritional intervention. Methods The information of children with hand-foot-mouth disease in three hospitals in Guilin area was collected by ifxed-spot continuous sampling. Inquiry investigations, physical mea-surements combined with clinical diagnosis were undertaken, and nutritional risk assessment and management were con-ducted by the malnutrition screening tool of children (STAMP scoring). Those with STAMP scores ≥4 were considered at high nutritional risk. Nutritional risk reassessment was conducted on children with high nutritional risk after nutritional intervention and management. Results A total of 192 children with hand-foot-mouth disease were selected. The occur-rence rate of high nutritional risk was 68.75%(132/192). The hospitalization time of patients with high nutritional risk was prolonged and the hospitalization expense was increased apparently. The nutritional support treatment and nutritional edu-cation were undertaken on the children with high nutritional risk. The incidence of high nutritional risk from admission to discharge decreased from 68.75%to 36.98%(P<0.05). The clinical outcomes of those children accepting nutritional inter-vention were signiifcantly improved (P<0.05). Conclusions The occurrence and prognosis of hand-foot-mouth disease is closely related to the nutritional status of children, so nutritional risk assessment, nutritional intervention and management should be performed as early as possible.%目的评价分析手足口病患儿的营养风险，探索合理可行的营养干预方案。方法采用定点连续抽样方法，收集桂林地区3所医院中手足口病患儿；采用询问调查、体格测量并结合临床诊断，采用儿童营养不良筛查工具（STAMP评分）进行营养风险评估与管理，以STAMP评分≥4分为存在高度营养风险。对存在高营养风险患儿实施营养干预和管理后再进行营养风险评估。结果共有192例手足口病患儿入选，存在高营养风险的发生率为68.75%（132/192）。有高营养风险的手足口病患儿住院时间延长，住院费用明显增加。对有高营养风险患儿进行营养支持治疗或营养健康教育，高营养风险发生率从入院时的68.75%下降至出院时的36.98%，差异有统计学意义（P<0.05），接受营养干预的手足口病患儿临床结局改善显著，差异有统计学意义（P<0.05）。结论手足口病发病和预后与患儿营养状况密切相关，应及早进行营养风险评估、干预和管理。
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