绵阳市丙型肝炎感染调查报告

摘要

目的 了解绵阳市丙型肝炎病毒(HCV)感染情况,为丙型肝炎的防治提供科学依据.方法 用酶联免疫吸附试验(ELISA)对前来绵阳市人民医院就诊的32 812例住院、门诊病人进行抗-HCV检测,并对其感染状况进行分析.结果 检测32 812例人群中,抗-HCV阳性630例,总感染率为1.89%,其中男性检测者17 341例,抗-HCV阳性336例,感染率为1.94%,女性检测者15 471例,抗-HCV阳性294例,感染率为1.90%;其中20岁以下检测3 127例,抗-HCV阳性26例,感染率为0.83%,20～40岁检测15 206例,抗-HCV阳性227例,感染率为1.49%,40岁以上检测14 479例,抗-HCV阳性377例,感染率为2.60%.结论 调查结果显示绵阳市HCV的感染率为1.89%,低于全国HCV感染率;在已感染人群中,男、女性患者所占比率无显著差异.人类感染HCV后导致肝脏慢性炎症坏死和纤维化,可发展为肝硬化甚至肝细胞癌,对患者的健康和生命危害极大,故对HCV进行实验室早检测早治疗非常重要.%Objective To explore the situation of hepatitis C ( 11CV ) infection in Mianyang City, and to provide scientific basis for prevention of hepatitis C in this area. Methods Serum samples of 32 812 inpatients and outpatients in this hospital were examined for anti - 11CV antibody by using enzyme - linked immunosorbent assay ( EL1SA ), and the situation of infection had been analyzed. Results Among these 32 812 cases, anti - 11CV antibody was positive in 630 cases, the total infection rate was 1. 89% , the detection in 17341 male cases, anti - 11CV antibody was positive in 336 cases, the infection rate was 1. 94% , the detection in 15 471 female cases, anti - 11CV antibody was positive in 294 cases , and the infection rate was 1. 90% . Among 3127 patients with age range below 20 years, anti - 11CV antibody was positive in 26 cases with infection rate of 0. 83% , in 15206 patients with 20 -40 years old, anti - 11CV antibody was positive in 227 cases with infection rate of 1.49% , in 14479 patients above 40 years old, anti - 11CV antibody was positive in 377 cases with infection rate of 2. 60% . Conclusion The above - mentioned findings suggested that the incidence rate of 11CV infection in Mianyang City was 1. 89% , it is lower than the nationwide incidence rate of 11CV infection, but there is a rising trend year by year. Among the infected population, male and female patients have no obvious difference. Human infection with 11CV leads to chronic hepatitis and fibrosis, thus it can progress to cirrhosis and hepatocellular carcinoma, it is a great risk to health and life of patients, so early detection and treatment of 11CV infection is very important in public health care.