Objective To evaluate the correlation of tumor chemotherapy related adverse reaction knowledge training and clinical out-comes. Methods This research enrolled 78 resident doctor to participate the correlation of tumor chemotherapy related adverse reaction knowledge training and clinical outcomes. The resident doctors were assigned to the control and test group according to the grade. The resident doctor in con-trol group accepted the routine course and the test group was accepted the routine course and tumor chemotherapy of gastrointestinal adverse reac-tions knowledge training. Finally,the objective clinical examination(OCE)and gastrointestinal adverse reaction occurrence,treatment and out-come were used to evaluate the quality of teaching course. Results In the each subject examination of OCE,the scores in test group were the same as in the control group. The subjects of adverse reactions of chemotherapy,the test group was significantly higher than that of control group( P <0. 05). The test group adverse reactions such as nausea,vomiting,and constipation were significantly lower than the control group. The hospitali-zation date extension,delayed chemotherapy,chemotherapy dose reduction,and termination of chemotherapy because of gastrointestinal adverse reactions of test groupˊs patients were significantly decreased than the control group. Conclusion Through strengthening the gastrointestinal adverse reaction knowledge training,the resident doctor could reduce the influence of the gastrointestinal adverse reaction to clinical treatment.%目的：通过对住院医师进行肿瘤化疗相关消化道不良反应的知识培训，探讨该教育模式与患者临床转归的相关度。方法即将进入肿瘤科轮转的78名住院医师1：1分配至对照组或实验组，两组均参与现有的肿瘤科常规培训，实验组同时加入肿瘤化疗相关的消化道不良反应知识培训；最后教学质量的评价通过客观性临床考试以及患者的化疗所致消化道不良反应发生、处理以及转归情况来评定。结果两组客观性临床考试总成绩差异无显著统计学意义（ P ＞0.05），在化疗消化道不良反应单独科目中，实验组成绩显著高于对照组（ P ＜0.05）；且临床治疗中患者恶心、呕吐以及便秘不良反应的发生率实验组明显低于对照组（ P ＜0.05）；实验组因胃肠道不良反应导致住院日期延长、推迟化疗、化疗剂量减量甚至中止化疗等情况较对照组明显减少。结论通过对住院医师加强肿瘤化疗消化道不良反应的培训课程，可以提高该不良反应患者的临床转归度。
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