生长抑素与前列地尔联合治疗对高脂血症性急性胰腺炎患者血小板、消化功能的影响

摘要

Objective To study the influence of somatostin combined with alprostadil on the platelet related indexes and digestive function of patients with acute hyperlipoidemia pancreatitis. Methods 86 patients with acute hyperlipoide - mia pancreatitis in our hospital from Feb 2013 to Feb 2015,were randomly divided into control group and treatment group with 43 cases in each group. The control group was treated with con-ventional treatment method;the treatment group was treated with domestie somatostin combined with alprostadil based on the treatment of the con-trol group. After treatment,the treatment effect,platelet related indexes and digestive function of two groups was compared. Results Total effec-tive rate of treatment group was 95. 3% ,was higher than that of the control group 76. 7%( P < 0. 05). And at 1st,3rd and 7th day after treat-ment,the platelet related indexes of treatment group were all lower than those of the control group,digestive function of patients in treatment group were all better than those of control group( P < 0. 05). Conclusion Somatostin combined with alprostadil is a new way in healing patients with acute hyperlipoidemia pancreatitis,and improve remarkably the platelet related indexes and digestive function and can reduce time of therapy.%目的：研究生长抑素与前列地尔联合治疗对高脂血症性急性胰腺炎患者血小板和消化功能的影响。方法2013年2月至2015年2月治疗的86例高脂血症性急性胰腺炎患者，将其随机分为对照组和治疗组，每组43例。对照组采用常规的治疗方法，治疗组在对照组的基础上加用生长抑素联合前列地尔治疗。比较两组患者的治疗效果，血小板相关指标和消化功能相关指标。结果治疗后，治疗组的治疗总有效率95.3%高于对照组的76.7%，差异有统计学意义（ P ＜0.05）。治疗后1 d，3 d 和7 d 的血小板相关指标治疗组均低于对照组，消化功能相关指标也均优于对照组，差异有统计学意义（ P ＜0.05）。结论生长抑素联合前列地尔能够显著改善血小板指标和消化功能相关指标，治疗高脂血症性胰腺炎效果显著，有效减少治疗时间，是治疗高脂血症性急性胰腺炎的新方法。