升血小板胶囊配合护理干预治疗特发性血小板减少性紫癜

摘要

目的：探讨升血小板胶囊配合护理干预措施对特发性血小板减少性紫癜（ ITP ）的临床意义。方法将52例ITP患者随机分为观察组和对照组，各26例，对照组单用泼尼松1 mg/（ kg·d），连续服用3个月，并配合常规护理模式进行干预；观察组在对照组基础上予升血小板胶囊4粒/次，3次/d，连续服用3个月，并以循证理念为指导制订护理干预措施，观察2组血小板（ PLT）恢复时间，采用抑郁自评量表（ SDS）进行抑郁评价，焦虑自评量表（ SAS ）进行焦虑评价，疗程结束后进行疗效评定。结果观察组 PLT 计数恢复至30×109/L、50×109/L、100×109/L时间均少于对照组（ P﹤0.05）；随着治疗及护理干预时间延长，焦虑和抑郁情绪阳性状态发生率逐渐降低，且观察组明显优于对照组（ P﹤0.05）；观察组总有效率为92.3％，明显优于对照组的69.2％（P﹤0.05）。结论在循证理念干预护理的基础上，升血小板胶囊联合激素治疗ITP，可有效的改善患者焦虑和抑郁情绪，使患者能够更好的配合治疗，有效的增加PLT计数，改善临床症状。%Objective To explore the clinical significance of Sheng Xuexiaoban capsules in combined with nursing interventions in the treatment of idiopathic thrombocytopenic purpura( ITP). Methods A total of 52 patients with ITP were randomized into the observation group and the control group. The patients in the control group were given predni-sone 1 mg/( kg·d),continuously for 3 months,in combined with the conventional nursing model for intervention;The patients in the observation group were given prednisone 1 mg/( kg · d ),and Sheng Xuexiaoban capsules,4 capsules/time,3 times/d,continuously for 3 months,in combined with nursing intervention in the guidance of evidence-based ide-a. The recovery time of PLT in the two groups was observed. SDS was used for depression evaluation,SAS for anxiety e-valuation,and efficacy evaluation was performed after the course being finished. Results The time for PLT count recov-ering to 30 × 109/L,50 × 109/L,and 100 × 109/L in the observation group was significantly less than that in the control group(P﹤0. 05). With the treatment and nursing intervention timing extending,the occurrence rate of the positive sta-tus of anxiety and depression was gradually reduced,and that in the observation was significantly superior to that in the control group(P﹤0. 05). The total effective rate in the observation group(92. 3%)was significantly superior to that in the control group(69. 2%)(P﹤0. 05). Conclusion On the basis of evidence-based nursing intervention,Sheng Xuexiaoban capsules in combined with hormone in the treatment of ITP can effectively improve the anxiety and depres-sion,which can render the patients’better coordination,effectively increase PLT count,and improve the clinical symp-toms.