气管拔管前应用右美托咪定对甲状腺手术患者麻醉复苏的影响

摘要

目的：：观察甲状腺手术患者全麻气管拔管前静脉泵注右美托咪定( DEX)对麻醉复苏的影响。方法：74例甲状腺手术患者随机分为观察组和对照组各37例,观察组术毕10 min时静脉泵注DEX 0.5μg/kg 10 min,对照组以0.9%氯化钠注射液10 ml同时间泵完。比较2组患者血压、心率、脉搏和血氧饱和度变化、术毕清醒睁眼时间及拔管时间,记录气管拔管前患者呛咳、恶心、呕吐等不良反应发生情况和术后1~4 h舒适评分( BCS)及痛觉模拟评分( VAS)。结果：2组患者术毕拔管时间差异无统计学意义(P>0.05)；观察组在泵注DEX后心率有所减慢(P0. 05). The HR in the observation group decreased after injecting DEX. Compared with the observation group, the incidence of cough in control group was high,and its BP and HR increased significantly at the time of extubation(P<0. 05 to P<0. 01). Compared with the observation group, the postoperative 1 to 4 h BCS and VAS in control group were low and high,respectively(P<0. 05). Conclusions:The DEX injection in thyroid surgery patients during extubation has good analgesic and sedative effects, which can effectively reduce the incidence of cough,and improve the comfortable degree of patients after operation.