薄棉灸配合围刺治疗带状疱疹疗效观察

摘要

目的：比较薄棉灸配合围刺与西药治疗带状疱疹(herpes zoster, HZ)的临床疗效差异。方法：将83例带状疱疹患者按入院先后顺序分为2组,薄棉灸组41例,西药组42例。薄棉灸组给予疱疹表面薄棉灸,辅以疱疹周围围刺治疗,每日治疗1次。西药组给予静脉滴注阿昔洛韦,每次0.25 g,每日1次；阿昔洛韦软膏涂擦患处每日3-5次。治疗10 d后,比较两组患者水疱开始吸收时间、结痂时间、疼痛减轻时间、显效时间、皮损愈合时间及后遗神经痛发生率。结果：治疗过程中,薄棉灸组脱落1例,西药组脱落2例。薄棉灸组愈显率为92.5%,总有效率为97.5%；西药组愈显率为72.5%,总有效率87.5%,两组愈显率及总有效率差异均有统计学意义(P＜0.05)。薄棉灸组患者疱疹开始吸收时间、结痂时间、疼痛减轻时间、显效时间、皮损愈合时间均明显低于西药组(P＜0.05)。薄棉灸组后遗神经痛发生率为2.07%,显著低于西药组的9.19%(P＜0.01)。结论：薄棉灸配合围刺治疗HZ疗效优于阿昔洛韦,且能明显降低后遗神经痛的发生率。%Objective:To compare the clinical efficacies between thin-cotton moxibustion plus surround needling and Western medication in treating herpes zoster (HZ). Methods:Eighty-three HZ patients were divided into two groups according to their admission sequence, 41 cases in the thin-cotton moxibustion group and 42 cases in the Western medication group. The thin-cotton moxibustion group received thin-cotton moxibustion on the surface of lesions plus surround needling around the lesions, once a day. The Western medication group was intervened by Acyclovir intravenous injection, 0.25 g per dose, once a day, along with external application of Acyclovir cream 3-5 times a day. After 10-day treatment, the blister-healing time, crusting time, pain-reducing time, onset time of action, lesion-healed time, and occurrence of post-herpetic neuralgia (PHN) were compared. Results:During the study, a case dropped out in the thin-cotton moxibustion group, and 2 cases dropped out in the Western medication group. The recovery and markedly-effective rate was 92.5% and total effective rate was 97.5% in the thin-cotton moxibustion group, versus 72.5% and 87.5% in the Western medication group, and the between-group differences were statistically significant (P<0.05). The blister-healing time, crusting time, pain-reducing time, onset time of action and lesion-healed time in the thin-cotton moxibustion group were significantly shorter than those in the Western medication group (P<0.05). The occurrence rate of PHN was 2.07% in the thin-cotton moxibustion group, significantly lower than 9.19% in the Western medication group (P<0.01). Conclusion:Thin-cotton moxibustion plus surround needling can produce a more significant efficacy than Acyclovir in treating HZ, and it can markedly reduce the occurrence of PHN.