摘要：目的：探讨重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白联合醋氯芬酸缓释片治疗类风湿性关节炎的临床疗效。方法选择2014年12月至2016年1月本院类风湿性关节炎患者103名，随机分为对照组、实验组，对照组给予重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白25mg，每周注射2次；实验组在注射重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白治疗的基础上再给予口服醋氯芬酸缓释片0.1g，每天两次。4周，8周疗程观察对比患者治疗前和治疗后的晨僵时间、患者关节疼痛VAS评分、患者关节肿胀指数、患者触痛关节指数、日常生活能力，观察患者临床疗效。结果临床研究结果表明4周，8周疗程后实验组的有效率明显高于对照组的有效率。另外，患者膝关节疼痛评分、肿胀指数、触痛指数均较治疗前明显改善，所有比较均有统计学意义P<0.05。结论重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白联合醋氯芬酸缓释片治疗类风湿性关节炎治疗效果安全可靠，值得在临床上推广。%Objective to investigate clinical effects of recombinant human tumor necrosis factor receptor Ⅱ- antibody fusion protein combined with Aceclofenac sustained-release tablets in treatment of rheumatoid arthritis.Methods choose 103 cases rheumatoid arthritis arthritis patients treated in our hospital from December 2014 to January 2016, randomly divide them into control and experimental group. Control group were treated with recombinant human tumor necrosis factor receptor Ⅱ 25mg, twice injections weekly; and experimental group with oral Aceclofenac sustained-release tablets 0.1g on the basis of recombinant human tumor necrosis factor receptor II, twice a day. After 4 and 8 weeks treating course, observe and compare patients before and after treatment with time of morning stiffness, joint pain VAS score, joint swelling index, joint tenderness index, daily living ability, and observe clinical curative effect of patients. Results clinical results showed effective rate of experimental group was significantly higher than control group after 4 and 8 weeks treating course. Also knee joint pain score, swelling index, tenderness index changed greatly compared with that before treatment, and all comparisons showed statistical significance (P< 0.05).Conclusion recombinant human tumor necrosis factor receptor Ⅱ - antibody fusion protein combined with Aceclofenac sustained-release tablets has safe and reliable effect for rheumatoid arthritis, which is worthy of clinical promotion.
摘要：Objective to discuss curative effect and safety analysis of paclitaxel liposomes and cisplatin combined with radiotherapy for malignant tumor.Methods choose 90 cases malignant tumor patients treated in our hospital from January 2013 to October 2015, and divided them into control and observation group according to random number method. Control group was treated with cisplatin only, while observation group with paclitaxel liposome combined with cisplatin. Compare treatment effect of two groups after radical radiotherapy threapy.Results total effective rate, 1 and 2-year survival rate and complication incidence of observation group was significantly higher than control group (P<0.05).Conclusion paclitaxel liposome plus cisplatin combined with radiotherapy has significant clinical effect for malignant tumor, which can effectively improve survival rate of patients,and reduce complication incidence.%目的：探讨紫杉醇脂质体加顺铂联合放疗治疗恶性肿瘤的疗效及安全性。方法选取我院2013年1月至2015年10月收治的90例恶性肿瘤患，按照随机数字法分为对照组与观察组。其中对照组采用单一顺铂进行治疗，而观察组采用紫杉醇脂质体联合顺铂进行治疗。两组患者同时进行根治性放疗方案，比较两种方式的治疗效果。结果观察组恶性肿瘤患者的治疗总有效率、1年存活率及2年存活率及并发症发生率明显优于对照组恶性肿瘤患者（P<0.05)。结论紫杉醇脂质体加顺铂联合放疗治疗恶性肿瘤具有显著的临床疗效，能够有效提高患者的生存率，降低并发症发生率。
摘要：Objective By QCC management activities, improving ICU nursing staff hand hygiene complianceMethods Through set up QCC, the selected topic, plans, the present situation investigation and by analysis, goal setting, parsing, formulate management measures for its implementation, compared before and after nursing staff to carry out the QCC hand hygiene compliance. Results To carry out quality control circle activities, nursing staff hand washing compliance increased from 72% to 98%, difference is statistically significant(χ2=19.780,P<0.01).Conclusion The application of quality control circle effectively improve the nursing staff to wash their hands at once, interventions for reference which can be promoted.%目的：通过品管圈活动，提高我院急诊内科护理人员手卫生依从性。方法通过成立品管圈、选定主题、拟定计划、现状调查及要因分析、设定目标、解析、制定实施管理措施，比较开展品管圈活动前后护理人员手卫生依从性情况。结果开展品管圈活动后，护理人员洗手依从性从由72%上升到98%，差异具有统计学意义（χ2=19.780，P<0.01）。结论品管圈的应用有效提高了护理人员洗手依从性，干预措施可推广借鉴。
摘要：目的：研究分析内科胸腔镜与闭式胸膜活检对胸腔积液的诊断价值。方法选择我院2014年10月至2015年10月接收的不明原因胸腔积液患者94例作为研究对象，将患者分为两组，甲组和乙组，均为47例，应用内科胸腔镜对甲组患者进行诊断，应用闭式胸膜活检对乙组患者进行诊断，比较两组诊断的准确性。结果甲组病理诊断阳性率比乙组高，差异有统计学意义（P<0.05）；甲组恶性肿瘤诊断率与乙组存在较大差异，差异有统计学意义（P<0.05）；甲组结核诊断率与乙组的差异较小，无统计学意义（P>0.05）；甲组慢性炎症、胸膜坏死组织诊断率与乙组存在较大差异，差异有统计学意义（P<0.05）；甲组与乙组的并发症发生率差异较小，无统计学意义（P>0.05）。结论内科胸腔腔镜在复杂性胸腔积液中的诊断价值较高，操作简单，诊断准确性较高，值得推广应用。%Objective to study and analyze diagnostic value of internal medicine thoracoscope and closed pleural biopsy for pleural biopsy.Methods choose 94 cases pleural biopsy with unclear causes received in our hospital from October 2014 to October 2015 as study objects, divide them into group A and B, 47 cases in each. Group A was diagnosed with medical thoracoscopy, and group B with closed pleural biopsy. Compare diagnosis accuracy of two groups.Results Pathological diagnosis positive rate of group A is higher than group B, difference showed statistical significance (P< 0.05). Malignant tumor accuracy of group A showed big difference from group B, difference showed statistical significance (P< 0.05); tuberculosis diagnosis accuracy of group A showed smaller differences from group B without statistical significance (P> 0.05). Diagnosis accuracy of chronic inflammation, pleural tissue necrosis of group A has big difference from group B, difference showed statistical significance (P< 0.05). Complication incidence of group A showed smaller differences from group B without statistical significance (P>0.05).Conclusion medical thoracoscope has high diagnosis value and diagnosis accuracy for complicated pleural effusion with simple operation, which is worthy of promotion and application.
摘要：目的：探究微型外固定支架治疗复杂性跖趾骨骨折的临床效果。方法选取我院2013年10月至2014年12月收治的12例复杂性跖趾骨骨折患者，作为本次研究的对象。所有患者均实施微型外固定支架治疗，观察患者骨折愈合情况，足功能的优良率。结果平均随访时间为（7.5±0.4）月，随访过程所有患者骨折均得以愈合。结合X线片检查，患者骨折愈合的时间2个月~3个月。足功能按照Maryland评价，优良率为91.67%。结论复杂性跖趾骨骨折通过微型外固定支架治疗，临床效果较好。%Objective To explore the clinical effect of mini external fixation for the treatment of metatarsal and phalangeal fracture complexity.Methods in our hospital in October 2013 to 2014 - December 12 cases complexity of metatarsal and phalangeal fractures, as the object of the study. All patients were treated with mini external fixator, and the good rate of foot function was observed in patients with fracture healing.Results the average follow-up time was (7.5 + 0.4) months follow-up, all fractures were healed. Combined with X-ray examination, patients with fracture healing time of 2 ~3 months. Foot according to Maryland functional evaluation, the excellent rate was 91.67%.Conclusion The mini external fixation for the treatment of metatarsal and phalangeal fracture conclusion complexity, better clinical effect.
摘要：目的：探讨经皮肾穿刺与开放手术治疗肾脓肿疗效差异。方法选取2014年3月至2015年1月我院收治肾脓肿患者82例为研究对象，根据患者治疗方式分为经皮肾穿刺组和开放手术组，比较两组患者手术时间、术中出血量、住院时间及并发症发生情况。结果经皮肾穿刺组患者手术时间、术中出血量及住院时间均少于开放手术组，比较差异有统计学意义（P<0.05）。经皮肾穿刺组出血、感染及腹腔粘连并发症发生率均低于开放手术组，比较差异有统计学意义（P<0.05）。结论经皮肾穿刺治疗肾脓肿较开放手术可减少患者创伤，降低并发症发生率。%Objective Percutaneous renal biopsy and open surgical treatment of renal abscess difference in efficacy.Methods Select March 2014 - January 2015 in our hospital 82 patients with renal abscess for the study.Results After surgery percutaneous renal biopsy group time, blood loss and hospital stay were less than the open surgery group, the difference was statistically significant (P <0.05). the difference was statistically significant (P<0.05).Conclusion Percutaneous treatment of renal abscess compared with open surgery can reduce patient trauma, reduced the incidence of complications.
摘要：Objective To investigate the understand the cause of the secondary infection of varicella and provide reference for clinical diagnosis and treatment.Methods analysis on in our department in October 2010 to 2012 September diagnosis and treatment of varicella cases were retrospective analysis and summing up the characteristics of the infection of patients.Results varicella secondary infections are mainly set in 10 to 14 years of age.Conclusion strengthen varicella eruption period management, in children with early treatment intervention can effectively reduce the incidence of infection.%目的：探讨了解引起水痘继发感染的原因，为临床诊治提供参考。方法分析，对我科2010年10月至2012年9月诊治水痘病例进行回顾性分析，总结患者的感染特点。结果水痘继发感染病例主要集中在10至14岁；结论加强水痘出疹期管理，对患儿及早进行药物干预治疗可有效减少感染的发生。