目的 探讨反复流产与内分泌激素异常之间的关系.方法 对64例反复流产史患者进行卵泡期性激素水平及黄体期孕酮测定.对异常者给予相应治疗后再次妊娠,监测胚胎发育情况.结果 64例患者中内分泌激素水平异常者57例(89.1％).最常见是孕酮合并雌激素低(24例,占42.1％)、促黄体激素合并雄激素高(13例,占22.8％)和泌乳素高(9例,占15.8％).结论 反复流产与内分泌激素异常,特别是与黄体功能不全或类似多囊卵巢综合征(PCOS),有十分密切的关系.%Objective To evaluate the relationship between recurrent miscarriage and abnormal hormones. Methods Sex hormone and progesterone in luteal phase were detected in 64 patients with recurrent miscarriage. The pregnancy and embryonic development were monitored in those with abnormal sex hormone and progesterone in luteal phase after appropriate treatments were taken. Results There were 57 patients (89.1%) with abnormal endocrine hormones. The most common three kinds of abnormality were low estrogen combined with low progesterone in 24 cases(42.1%), high luteinizing hormone combined with high androgen in 13 cases(22. 8%) and high prolactin in 9 cases(15. 8%). Conclusion There is a very close relationship between recurrent miscarriage and abnormalities of endocrine hormones, especially in the patients with luteal phase defect or with the similarities to polycystic ovary syndrome(PCOS).
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