Objective To investigate the application value of corrected modified early warning score(MEWS) in evaluating the severity of patients with severe acute pancreatitis (SAP). Methods Taking the endings on 30 days after admission as the prognostic results,forty-two SAP patients were evaluated by corrected MEWS and MEWS at the same time. Results The scores given by corrected MEWS were higher than those by MEWS in SAP patients who were survival(30 cases) and died (12 cases)[(4. 7 ± 1. 6) points and (12.9±2.3) points vs. (2.9±1.2) points and (8.2±1.8) points](P<0. 05). Taking death as a predictor, the area under ROC curve was greater calculated by corrected MEWS than that calculated by MEWS (P<0. 05). The sensitivity and specificity of corrected MEWS were 100.0%, and 4. 7%, respectively, which were significantly different from 87. 2 % and 11. 3 % of MEWS( P<0. 01). Conclusion Compared with MEWS, the corrected MEWS is more accurate in reflecting the severity and predicting the mortality for the patients with SAP.%目的 探讨妊娠滋养细胞肿瘤的临床特点、治疗方法及转归.方法 妊娠滋养细胞肿瘤患者105例,年龄18-54岁；绒癌34例,侵蚀性葡萄胎71例.根据预后评分的低危或高危分别选择单药或联合化疗3-11个疗程,部分患者辅以介入治疗.19例接受了全子宫切除术.结果 105例中,单纯化疗及化疗联合手术患者完全缓解94例(89.5％).其中,86例单纯化疗患者完全缓解78例(90.7％),19例化疗联合手术完全缓解16例(84.2％).不同FIGO分期患者的完全缓解率:Ⅰ期完全缓解率100.0％(62/62),Ⅱ期完全缓解率100.0％(23/23);Ⅲ期完全缓解率53.3％(8/15),Ⅳ期完全缓解率25.0％(1/5).结论 早期诊断和及时化疗,有手术指征者联合手术,可使妊娠滋养细胞肿瘤获得满意的治疗效果.
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