硫酸镁联合尼莫地平治疗妊娠高血压的临床效果

摘要

Objective To investigate the clinical efficacy of magnesium sulfate combined with nimodipine in the treatment of pregnancy-induced hypertension.Methods 80 patients with pregnancy-induced hypertension treated at our hospital from March,2012 to March,2015 were selected and were randomly divided into an observation group and a control group,40 cases for each group.The control group were treated with magnesium sulfate and other conventional methods for 1 month.The observation group were treated with magnesium sulfate nimodipine for 1 month.The clinical efficacies were evaluated and compared.Results After the treatment,the blood pressure conditions were obviously improved in the observation group and were better in the observation group than in the control group.The total efficacy was 95.5％ in the observation group and was 71.4％ in the control group,with a statistical difference (P＜0.05).After childbirth,the neonatal conditions were better in the observation group than in the control group,with statistical differences(P＜0.05).There were statistical differences in pregnancy outcomes between these two groups (P＜0.05).Conclusions Magnesium sulfate combined with nimodipine in the treatment of pregnancy-induced hypertension is effective and safe and worth being clinically studied and generalized.%目的 探讨硫酸镁联合尼莫地平治疗妊娠期高血压的临床效果.方法 选取2012年3月至2015年3月于本院治疗的80例妊娠高血压患者,将其随机分为观察组与对照组,各40例.对照组采用硫酸镁以及其他常规方法治疗,观察组则采用硫酸镁联合尼莫地平治疗,两组均治疗1个月.评定、对比两组临床疗效.结果 经过长期有效的治疗,观察组血压状况得到明显改善,远超对照组(P＜0.05);观察组总有效率为95.5％,对照组为71.4％,差异有统计学意义(P＜0.05).分娩后观察组新生儿状况优于对照组,差异有统计学意义(P＜0.05);观察组与对照组妊娠结局差异有统计学有意义(P＜0.05).结论 硫酸镁联合尼莫地平治疗妊娠期高血压症效果明显,具有一定的安全性,值得临床进一步研究与推广.