首页> 外国专利> Specific marker genes for diagnosing pregnancy-induced hypertension and methods for analyzing gene expression levels related to pregnancy-induced hypertension using the specific marker genes

Specific marker genes for diagnosing pregnancy-induced hypertension and methods for analyzing gene expression levels related to pregnancy-induced hypertension using the specific marker genes

机译:诊断妊娠高血压综合征的特定标记基因以及使用该特定标记基因分析与妊娠高血压相关的基因表达水平的方法

摘要

The present invention relates to a diagnostic marker gene specific for preeclampsia and a method for analyzing preeclampsia-related gene expression using the same, and analyzes a preeclampsia-related gene expression using a marker gene for increasing the accuracy of predicting preeclampsia risk in pregnant women. The preeclampsia related gene expression analysis method of the present invention comprises the steps of preparing the RNA of the pregnant woman, the expression level of at least one gene selected from the group consisting of OXGR1, GALK2 and HBG2 genes specific for preeclampsia from the prepared RNA. And measuring the difference between expression of at least one gene selected from the group consisting of the OXGR1, GALK2, and HBG2 genes, expression level, and expression level with the normal group. Therefore, the present invention can predict the risk of preeclampsia in pregnant women early.;Preeclampsia, marker genes, risk prediction, gene expression patterns, early prediction
机译:本发明涉及特异于子痫前期的诊断标志物基因和使用其分析子痫前期相关基因表达的方法,并使用标志物基因分析子痫前期相关基因表达以提高预测孕妇子痫前期风险的准确性。本发明的子痫前期相关基因表达分析方法包括以下步骤:制备孕妇的RNA,从制备的RNA中选择至少一种选自子痫前期特异性基因的基因GROX1,GALK2和HBG2的表达水平。 。并且测量正常组中选自OXGR1,GALK2和HBG2基因的至少一种基因的表达,表达水平和表达水平之间的差异。因此,本发明可以早期预测孕妇先兆子痫的风险。;先兆子痫,标志物基因,风险预测,基因表达模式,早期预测。

著录项

  • 公开/公告号KR101073653B1

    专利类型

  • 公开/公告日2011-10-14

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20090026799

  • 申请日2009-03-30

  • 分类号C12N15/11;C12Q1/68;G01N33/52;

  • 国家 KR

  • 入库时间 2022-08-21 17:49:38

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