卵巢癌的MR分子成像研究进展

摘要

Ovarian cancer is a common malignant tumor with the highest mortality in female individuals. Early diagnosis is a challenge for clinicians. It is crucial to improve the accuracy of the diagnosis. The development and application of MRI make it possible to make an early diagnosis and facilitate the consequent targeted therapy for ovarian cancer. In this review we mainly focused on the choice of target spots in molecular imaging technology and specific contrast medium of MRI. Moreover, the targeted therapy in ovarian cancer with MRI molecular imaging technology and the monitoring of prognosis were reviewed.%卵巢癌在女性恶性肿瘤中死亡率高，早期诊断困难，提高卵巢癌早期诊断准确率至关重要。近年来MR分子成像技术的开发及应用，为卵巢癌的早期诊断及后续的靶向治疗提供了可能。就卵巢癌分子成像的靶点选择及MR特异性对比剂的研究进展进行论述，并进一步对MR分子成像应用于卵巢癌靶向治疗及其疗效检测做出展望。