二尖瓣置换术后凝血功能测定的临床价值

摘要

目的：探讨二尖瓣置换术（MVR）后患者凝血功能的变化及临床价值。方法将2012年1月至2014年1月期间收治入该院进行 MVR 后患者163例纳入观察组，将同期来该院同期健康体检者163例纳入对照组，检测两组患者的凝血酶原时间（PT ）、部分活化凝血酶原时间（APT T）、纤维蛋白原（FIB）浓度、凝血酶时间（TT ）和凝血酶原时间国际标准化指数（INR），并进行统计学分析。结果观察组大多数 PT 、APTT 、INR 均明显高于对照组，差异有统计学意义（P＜0．05）。结论 MVR 后患者定期测定凝血功能可以有效反映患者体内抗凝及凝血机制紊乱的现状，可提高诊断及治疗的效率和临床预测价值。%Objective To investigate the changes and clinical significance of the coagulation function after mitral valve replace‐ment (MVR) .Methods 163 cases of MVR admitted in our hospital from January 2012 to January 2014 were included in the obser‐vation group and contemporaneous 163 individuals of healthy physical examination were selected as the control group .The pro‐thrombin time (PT) ,activated partial thromboplastin time (APTT ) ,fibrinogen concentration (FIB) ,thrombin time (TT ) and pro‐thrombin time international normalized ratio (INR) in the two groups were detected and the detected results were performed the statistically comparative analysis .Results PT ,APTT and INR in the majority of the observation group were significantly higher than those in the control group ,the differences had statistical significance (P < 0 .05) .Conclusion The regular determination of blood coagulation function after MVR can effectively reflect the disorder status of anticoagulant and coagulation mechanism ,and can improve the efficiency of diagnosis and treatment and clinical predictive value .