稀土双膦酸酯配合物和稀土氯化物对Mannich反应的催化作用

摘要

研究了Dy(OTf)3、DyCl3和稀土双膦酸酯配合物{[Dy(OTf)2L2(H2O)2](OTf)(CH3CN)}[L=(iPrO)2P(O)CH2P(O)(iPrO)2]等对Mannich反应的催化作用,发现以Dy(OTf)3为催化剂时,收率为54%,[Dy(OTf)2L2(H2O)2](OTf)(CH3CN)的收率仅为8%,OyCl3收率达47%.研究了12种稀土金属氯化物对Mannich反应的催化作用,其中,ErCl3催化剂的收率最高,达到61%.%The catalytic behaviors of Dy (OTf)3, DyCl3 and rare earth diphosphonate complex {[Dy(OTf)2L2(H2O)2](OTf)(CH3CN)}[L=(iPrO)2P(O)CH2P(O)(iPrO)2] were studied for Maanich reactions. The results showed that the yield of 54% ,8% and 47% were obtained over Dy(OTf)3, [Dy(OTf)2L2(H2O)2](OTf)(CH3CN) and DyCl3, respectively. Among the twelve rare earth chlorides involved, ErCl3 attained the maximum yield 0f 61% for Mannich reactions.