雷珠单抗治疗视网膜静脉阻塞引起的黄斑水肿的3+PRN 治疗方案的临床疗效观察

摘要

Objective To observe the clinical effect of the treatment of macular edema caused by retinal vein occlusion in the treatment of retinal vein occlusion caused by 3+PRN. Methods 13 patients with venous obstruction (13 eyes) treated with 3+PRN were retrospectively analyzed. All patients were followed up for 12 months. The changes of and BCVA before and after January, CMT and, and the number of IVR injections in 12 months. The occurrence of complications or adverse reactions during the treatment was observed. Results 12 months after treatment, CMT and P<0.05 were compared with each other in the treatment time, BCVA had significant difference. Average injection times were 5.25 times. No complications or adverse reactions occurred during the treatment and follow-up. Conclusion 3+PRN therapy can significantly treat macular edema caused by RVO, reduce the risk of injection and reduce the economic burden of patients.%为了观察雷珠单抗玻璃体腔注射3+PRN 方案治疗视网膜静脉阻塞引起的黄斑水肿的临床疗效，探讨适合视网膜静脉阻塞患者的优化治疗方案。通过回顾分析13例静脉阻塞患者（13只眼）行3+PRN 治疗。所有患者均完成12个月随访。统计治疗前后1月-12月的 BCVA、CMT 的变化情况，统计12个月内 IVR 注射次数。治疗过程中密切观察并发症或不良反应的发生。显示，随诊12个月，治疗前后各随诊时间内 BCVA、CMT 比较，P<0.05有统计学差异。平均注射次数为5.25次。在治疗及随访过程中均无并发症或不良反应发生。证明3+PRN 治疗，能显著治疗 RVO 引起的黄斑水肿，降低注射风险，并减少患者的经济负担。