强化胰岛素治疗危重症患者应激性高血糖的临床疗效观察

摘要

目的：探讨危重症应激性高血糖（ SHG ）强化胰岛素治疗方案的疗效。方法：将120例危重症SHG患者随机分为强化胰岛素治疗组和常规治疗组各60例，观察两组治疗效果。结果：强化治疗组血糖水平均低于常规治疗组，P＜0．05；强化治疗组患者ICU治疗时间，抗生素使用时间，呼吸机使用时间，泵入胰岛素时间等优于对照组，均P＜0．05。两组治疗并发症主要包括院内感染和低血糖，其中，强化治疗组院内感染发生率低于对照组，P＜0．05；两组低血糖发生情况差异比较无统计学意义；两组死亡率比较差异有统计学意义，P＜0．05。结论：强化胰岛素治疗危重症SHG，具有较好的疗效，能有效降低并发症发生的几率，降低死亡率，临床疗效明显。mortality．%Objective:To investigate the clinical efficacy of intensive insulin therapy for 60 cases criti-cally ill patients with stress hyperglycemia .Method:120 cases of critically ill patients were randomly divided into SHG intensive insulin therapy group and the conventional treatment group (60 cases, respectively), and the effect were observed .Result: The blood glucose levels of the intensive therapy group were statistically lower than those of the conventional treatment group ( P<0.05 ) .The ICU treatment time , antibiotics use time, ventilation time and insulin pump time of the intensive therapy group were better than those of the con -trol group, all P<0.05.The complications included hypoglycemia and nosocomial infections , and the inci-dence of the both complications of the intensive therapy group were lower than that of the control group , ( P<0.05).There was statistically significant of the mortality rate between the two groups , (P<0.05).Conclu-sion:The clinical efficacy of intensive insulin therapy for 60 cases critically ill patients with stress hypergly-cemia is satisfactory , which could effectively reduce the probability of occurrence of complications and reduce mortality.