Objective To evaluate the pregnancy outcome in the early pregnancy by measuring endometrial volume and thickness, and the number of endometrial vascular with transvaginal three-dimensional (3D) ultrasound. Methods 87 pregnant women with no intrauterine gestational sac observed were selected, and detected for endometrial volume and thickness, the number of endometrial vascular with two-dimensional and three-dimensional ultrasound. According to the results, the patients were divided into the early pregnancy group, the ectopic pregnancy group, and the early abortion group. Results The endometrial volume and thickness in the three groups showed no statistically significant difference. The sensitivity and specificity of the area under the ROC curve was 8.1 ml. The number of endometrial vascular was 1-5. Conclusion ROC curve has important clinical significance to the evaluation of pregnancy outcome in the early pregnancy of unknown location.%目的 评价经阴道三维(3D)超声测定子宫内膜容积、计数子宫内膜下血管条数在预测早早孕宫腔内未见孕囊时的妊娠结局.方法 选取87例妊娠试验阳性但宫腔内未见孕囊的孕妇,应用二维、三维超声测定子宫内膜的厚度和容积,并应用三维彩色多普勒计数子宫内膜下血管条数.一周后随诊,根据随诊结果分为早孕组、宫外孕组、早孕流产组,宫内孕为一周后复查见孕囊及卵黄囊、宫外妊娠均有术后病理结果证实、早孕流产组为复查宫内外未见孕囊,血清人绒毛膜促性腺激素(HCG)逐渐降至正常范围.结果 经阴道三维超声下内膜容积测量在确定不明位置早早孕的各受试者操作特性曲线(ROC曲线)下面积差异有统计学意义(P＜0.05)；选用敏感性与特异性之和最大者为最佳临界值为8.1ml.子宫内膜下血管为1～5条不等.结论 应用ROC曲线确定子宫内膜容积的最佳值,对诊断早早孕期不明位置妊娠的预测有重要的临床意义.
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