Objective To investigate clinical effect of subtotal thyroidectomy in the treatment ot bilateral nodular thyroid goiter.Methods A total of 103 patients with bilateral nodular thyroid goiter treated by subtotal thyroidectomy in our hospital were selected as the observation group,and 45 patients undergoing total thyroidectomy were enrolled as the control group.The clinical efficacy,complications and recurrence of the two groups were compared.Results The operation time,analgesic use,length of hospital stay were (83.6±22.4)min,(76.2±10.6)mg,(9.3±1.4)d in the observation group,and (113.2±24.7)min,(162.5±15.1)mg,(12.1±1.2)d in the control group,respectively,showing statistically significant difference between the two groups (P＜0.05).The proportion of temporary recurrent laryngeal nerve injury,temporary parathyroid damage,thyroid dysfunction were 2.9％,4.9％,1.9％ in the observation group,and 11.1％,15.6％,11.1％ in the control group,respectively,with statistically significant differences between the two groups (P＜0.05).The total effective rate of the observation group was 99.0％,which was not significantly different from that of the control group (100.0％),P＞0.05.Conclusion Subtotal thyroidectomy in the treatment of bilateral nodular thyroid goiter have good effect,with rapid postoperative recovery,shorter hospital stay,high cure rate,fewer complications,which is worthy to be used in clinical application.%目的 探讨甲状腺次全切除术治疗双侧结节性甲状腺肿的临床效果.方法 选择我院收治的采用甲状腺次全切术治疗双侧结节性甲状腺肿患者103例作为观察组,与同期采用甲状腺全切术45例患者作为对照组,比较两组疗效、并发症及复发情况.结果 观察组手术时间为(83.6±22.4)min、镇痛剂使用量为(76.2±10.6)mg、住院时间为(9.3±1.4)d,对照组分别为(113.2±24.7)min、(162.5±15.1)mg、(12.1±1.2)d,观察组手术时间、镇痛剂使用量、住院时间与对照组差异有统计学意义(P＜0.05)；观察组术后暂时性喉返神经损伤为2.9％、暂时性甲状旁腺损伤为4.9％、甲状腺功能减退为1.9％,对照组分别为11.1％、15.6％、11.1％,观察组的术后暂时性喉返神经损伤、暂时性甲状旁腺损伤、甲状腺功能减退的比例与对照组差异有统计学意义(P＜0.05)；观察组总有效率为99.0％,对照组为100.0％,两组术后疗效比较差异无统计学意义(P＞0.05).结论 甲状腺次全切除术治疗双侧结节性甲状腺肿疗效好,术后恢复较快、住院时间短、治愈率高、并发症少,值得临床应用.
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