超敏C反应蛋白与急性心肌梗死的相关性探讨

摘要

目的：探讨超敏C反应蛋白（hs-CRP）与急性心肌梗死的关系。方法收集2008年8月至2011年9月收住我院的52例冠心病患者的病历资料。其中心绞痛29例，急性心肌梗死23例，所有患者入院后当天检测hs-CRP。结果心肌梗死患者hs-CRP为(18.4±4.8) mg/L，明显高于心绞痛患者的(11.3±3.1) mg/L，差异有统计学意义(P<0.05)。hs-CRP判断急性心肌梗死ROC曲线下面积A (hs-CRP)=0.898，其判断急性心肌梗死的诊断阈值为23.2 mg/L，相应的敏感度(Se)为0.77，特异度(Sp)为0.89。结论 hs-CRP可判断急性心肌梗死的发生，其阈值为23.2 mg/L。%Objective To explore the relationship between hyper-sensitive C reactive protein (hs-CRP) and acute myocardial infarction (AMI). Methods The clinical data of 52 patients with coronary artery disease (CAD) were enrolled in this study, which included 29 patients with angina pectoris (AP) and 23 patients with AMI. The blood examples of all patients were taken to check the concentration of hs-CRP. Results The concentration of hs-CRP in patients with AMI was (18.4 ± 4.8) mg/L, which is statistically significantly higher than that in patients with AP (11.3±3.1) mg/L. For AMI diagnosis, the area under ROC curve A (hs-CRP) for hs-CRP was 0.898. The diag-nosing threshold value was 23.2 mg/L. Se (sensitivity) was 0.77, and Sp (specificity) was 0.89. Conclusion AMI can be detected by hs-CRP, and the diagnosing threshold value is 23.2 mg/L.