Objective To investigate the syphilis infection status in unmarried ordinary labors in Bao’an Dis-trict of Shenzhen, and to analyze the risk factors, in order to provide reference for promoting and preventing syphilis knowledge, and strengthening the necessity of premarital syphilis detection. Methods A total of 5 183 labors from factories, construction sites and stations were enrolled in the study. 3~4 ml of venous blood of each respondent was collected, and toluidine red unheated serum test (TRUST) was employed to detected the early syphilis antibody in se-rum. The positive sera screened out were subjected to further treponema pallidum partical assay (TPPA) and chemilu-minescence immunoassay (CLIA). Diagnosis of syphilis infection was made by combining with clinical and epidemio-logical data. Results The total infection rate of syphilis of unmarried ordinary labors was 2.9% (148/5 183), with 2.0%(41/2 062) for males and 3.4%(107/3 121) for females. There was statistically significant differences between males and females (P<0.05). The total infection rate was 2.6%(75/2 857) in factories, 3.1%(42/1 342) in construc-tion sites, and 3.2% (31/984) in stations, which was slightly higher in construction sites and stations than factories (0.5%~0.6%), with no statistically significant difference (P>0.05). The positive rate of syphilis in people over 30 years old (3.9%) was significantly higher than that of people under 30 years old (2.7%), and the difference was statistically significant (P<0.05). The positive rate of people of elementary school (3.3%) and junior high school (2.8%) was signif-icantly higher than that of high school and technical secondary school (1.8%), and the difference was statistically sig-nificant (P<0.05). Conclusion Infection rate of syphilis of unmarried ordinary labors in Bao’an District of Shenzhen is relatively high. We should strengthen the syphilis harm and prevention knowledge propaganda, promote and strengthen the necessity of premarital syphilis detection, to reduce or eliminate the mutual spread in married couple and babies born with congenital syphilis.%目的：了解深圳宝安区普通劳务工未婚男女梅毒感染状况并分析其危险原因，为宣传和预防梅毒知识，加强男女婚前梅毒检测的必要性提供参考依据。方法随机抽查本区工厂、工地及车站等劳务工人员共5183例，采集受检者静脉血3~4 ml，采用甲苯胺红不加热血清试验(TRUST)方法进行梅毒抗体初筛，对筛选出的阳性标本再用梅毒螺旋体明胶凝集试验(TPPA)和化学发光免疫法同时进行确诊，结合临床资料和流行病学综合判断梅毒感染。结果普通劳务工未婚男女梅毒总感染率为2.9%(148/5183)，其中男性2.0%(41/2062)，女性3.4%(107/3121)，男女之间比较差异有统计学意义(P<0.05)；工厂为2.6%(75/2857)，工地为3.1%(42/1342)，车站为3.2%(31/984)，工地和车站场所梅毒感染率略高于工厂，两者差异无统计学意义(P>0.05)；30岁以上人群梅毒阳性率明显高于30岁以下的人群，差异有统计学意义(P<0.05)；小学(3.3%)和初中(2.8%)文化层次的人群明显高于高中及中专(1.8%)以上的人群，差异有统计学意义(P<0.05)。结论宝安区普通劳务工未婚男女梅毒感染率比较高，应加强梅毒危害及预防相关知识的宣传，提倡和加强必要的婚前检测，减少或杜绝婚后夫妻互相传播及先天性梅毒婴儿出生。
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