北细辛原粉及其不同提取物抗炎作用初探

摘要

目的 初步探讨北细辛原粉及其不同提取物的抗急性炎症作用.方法 采用巴豆油引起的小鼠耳肿胀法和角叉菜胶引起的大鼠足爪肿胀法,观察北细辛原粉及其不同提取物的抗急性炎症作用.结果 北细辛原粉低、中、高剂量组及北细辛挥发油低、中、高剂量组均有抑制小鼠耳肿胀作用;挥发油高剂量组还具有抑制及大鼠足趾肿的作用.结论 北细辛原粉及北细辛挥发油有抗急性炎症作用.%Objective To explore the roles of Asarum original powder and different extracts against acute inflammation. Methods The anti-inflammatory roles of of Asarum original powder and extracts were observed by investigating their effect against croton oil-induced mouse ear swelling and carrageenan-induced rat paw swelling. Results The Asarum original powder of low, medium and high dose and volatile oils of low, medium and high dose all can inhibit mouse ear swelling. Volatile oil of high dose can also inhibit rats paw swelling. Conclusion The Asa-rum original powder and volatile oil have anti-inflammatory effect.