早期肠内营养支持对重症急性胰腺炎患者机体免疫及营养状态的影响

摘要

Objective To investigate the influence of early enteral nutrition support on the body immune and nutritional state of patients with severe acute pancreatitis (SAP). Methods Sixty-eight patients with SAP in our hos-pital from April 2014 to March 2013 were randomly divided into two groups, with 34 cases in each group. The two groups were intervened with early enteral nutrition support (observation group) and parenteral nutrition support (con-trol group) based on conventional treatment. Then the body immune indexes and nutritional state indexes of two groups before treatment and at the first and second week after treatment were compared. Results The body immune and nutritional state of two groups before treatment had no statistically significant differences, while the body immune and nutritional state indexes of observation group at first and second week after treatment were all significantly better than those of control group. The detection results of two groups at the second week after treatment were all significant-ly better than those before treatment (P<0.05). Conclusion The influence of early enteral nutrition support on the body immune and nutritional state of patients with severe acute pancreatitis are more active, and it is worthy of clini-cal application.%目的：探讨早期肠内营养支持对重症急性胰腺炎(SAP)患者机体免疫及营养状态的影响。方法将2012年4月至2014年3月我院收治的68例SAP患者随机分为两组各34例，两组患者在常规治疗的基础上分别给予早期肠内营养支持(观察组)和肠外营养支持(对照组)，比较两组患者治疗前和治疗后l周、2周的机体免疫状态指标和营养状态指标。结果两组患者治疗前的机体免疫及营养状态无明显差异，但观察组在给予早期肠内营养支持l周和2周后的免疫及营养状态指标均优于对照组，且两组患者在给予治疗2周后明显优于治疗前，差异均有统计学意义(P<0.05)。结论将早期肠内营养支持应用于SAP患者中能有效改善患者机体的营养及免疫状态，影响效果更为积极，值得临床中推广应用。