脾脏是一个重要的免疫器官,它在抗感染、肿瘤免疫等方面有重要功能,脾切除可导致危及生命的感染以及其他免疫相关疾病.脾外伤、门脉高压脾功能亢进、血液系统疾病病理脾等都涉及脾切除与脾功能保留之间的问题.脾移植主要用于各种原因脾切除术后维持机体免疫力、预防并发症,亦有部分异体脾移植用于血液系统疾病和晚期肿瘤的研究与治疗.本文结合脾切除术后风险对脾移植术的进展做一综述.%The spleen is an important immune organ, which plays an important role in anti-infection, tumor im-munity, etc. Splenectomy can increase the risks of serious infections and other immune related diseases. There is a ques-tion how to keep the spleen function after splenectomy for spleen trauma, portal hypertension associated with hypersplen-ism, blood system diseases. Spleen transplantation is mainly used for maintaining the immunity and preventing complica-tions after splenectomy. There are also some studies of allogeneic spleen transplantation in the treatment of blood system diseases and advanced carcinoma. This paper reviews the risks of splenectomy and the progress of spleen transplantation.
展开▼
