Objective To observe the clinical effects of prophylactic cervical cerclage in patients with cervical incompetence (CIC). Methods A total of 134 patients with CIC in Department of Obstetrics and Gynecology, Maternal and Child Health Care Hospital of Longgang District of Shenzhen from September 2012 to August 2015 were randomly divided into the observation group and the control group according to the random number table, with 67 cases in each group. The observation group was treated with prophylactic cervical cerclage, and the control group was treated with expectant treatment. All patients were followed up to the end of pregnancy. Then term birth rate, abortion rate, prema-ture delivery rate, neonatal survival rate, and prolonged pregnancy were contrasted between the two groups,which were also contrasted between different time for cervical cerclage. Results Term birth rate, neonatal survival rate, pro-longed pregnancy time in the observation group were 67.2%, 95.5%, (14.2 ± 3.4) weeks, versus 10.4%, 58.2%, (7.3 ± 3.2) weeks in the control group (P<0.01). The abortion rate and premature delivery rate were 1.5%and 31.3%, signifi-cantly lower than 41.8%, 47.8%in the control group, (P<0.01 or P<0.05). Term birth rate, premature delivery rate in patients undergoing cervical cerclage in 12-16 weeks of pregnancy was 86.4%, 57.8%, versus 13.6%, 40.0%in 17-23 weeks (P<0.05). Conclusion Prophylactic cervical cerclage can effectively prolong the time of pregnancy and im-prove term yield and neonatal survival rate, and decrease the rate of abortion and premature delivery rate in patients with CIC, and also improve the quality of the population. The effect is better when cervical cerclage was implemented in 12-16 weeks of pregnancy, compared 17-23 weeks.%目的 观察预防性宫颈环扎术在宫颈机能不全(CIC)患者中的应用效果.方法 选取2012年9月至2015年8月期间深圳龙岗区妇幼保健院妇产科收治的134例CIC患者,以数字表法随机分为观察组和对照组,每组67例,观察组给予预防性宫颈环扎术治疗,对照组给予期待疗法,所有患者均随访至妊娠结束,比较两组患者的足月产率、流产率、早产率、新生儿存活率以及延长妊娠时间,同时对比不同时机宫颈环扎术对足月产率、流产率、早产率、新生儿存活率的影响.结果 观察组患者的足月产率、新生儿存活率分别为67.2%和95.5%,均显著高于对照组的10.4%和58.2%,妊娠延长时间为(14.2±3.4)周,显著长于对照组的(7.3±3.2)周,差异均有显著统计学意义(P<0.01);观察组患者的流产率、早产率分别为1.5%和31.3%,均明显低于对照组的41.8%和47.8%,差异均有统计学意义(P<0.05或0.01);观察组患者孕12~16周接受宫颈环扎术患者足月产率为86.4%,明显高于17~23周的57.8%,早产率为13.6%,明显低于17~23周的40.0%,差异均有统计学意义(P<0.05).结论 预防性宫颈环扎术用于CIC患者能够有效延长妊娠时间,提高足月产率与新生儿存活率,降低流产率与早产率,提高人口质量,且该手术早期实施效果更佳.
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