青龙衣煎膏剂对H22肿瘤小鼠抗肿瘤作用的实验研究

摘要

Objective To study the effect of anti-tumor and life prolonging rate in tumor mice of H22 type with Qinglongyi electuary. Method Establish model of tumor mice of H22 type, divided in 5 groups in random. The negative control group:saline group;the positive control group:Cisplatin group;the Qinglongyi electuary high (200 mg/kg), middle (100 mg/kg), low (50 mg/kg) dosage group. Compute the anti-tumor rate and life prolonging rate. Results It showed anti-tumor rate can reach 66.07%max, life prolonging rate 83.73%max. Conclusion The Qinglongyi electuary has obviously inhibited effect on H22 tumor cell, and the effect increased as dosage increased, and the survive time of mice was prolonged obviously.%目的：研究青龙衣煎膏剂对H22型肿瘤小鼠抑瘤作用及生命延长率的影响。方法建立H22型肿瘤小鼠模型，随机分为5组，雌雄各半，每组12只小鼠。分别为阴性对照组：生理盐水组；阳性对照组：顺铂组；青龙衣煎膏剂低（50 mg/kg）、中（100 mg/kg）、高（200 mg/kg）剂量组。计算抑瘤率、生命延长率。结果抑瘤率最高可达66.07%，生命延长率最高可达83.73%。结论青龙衣煎膏剂对H22生长有明显的抑制作用，且随剂量的增加而增强。并可明显延长小鼠的生存时间。