三七根中可分离出三七皂苷R1、R2、R3、R4、R5、R6和人参皂苷Rb1、Rd、Re、Rg1、Rg2、Rh1等多种单体皂苷成分，三七总皂苷含量高达12％。已经明确三七总皂苷和部分三七单体皂苷在抗肿瘤方面具有的多种活性：直接抑制肿瘤细胞、促肿瘤细胞凋亡、诱导肿瘤细胞分化、逆转肿瘤细胞多药耐药、抗肿瘤转移等作用。三七在抗肿瘤方面具有很大研究潜力与开发前景，如果能从细胞、分子，或基因水平上更深入进行研究，明确其抗肿瘤的多种机制，将对临床合理应用三七治疗肿瘤产生更重大意义。%From the root of Panax notoginseng Burk. F. H. Chen, we can extract many components, such as notoginsenoside R1 ,R2 ,R3 ,R4 ,R5 ,R6 ,and ginsenoside Rb1 ,Rd,Re,Rg1 ,Rg2 ,Rh1 , in which total Panax Notoginseng Saponins accounts for 12%. It is very sure that total Panax notoginseng saponins and part of notogensenoside are active for antineoplastic. They can treat against tumor from different aspects, such as inhibiting tumor cell directly, leading tumor cells apoptosis, inducing tumor cellular differentiation, reversing multidrug resistance, anti tumor metastasis, and so on. There are huge research potential and development prospect in anti-tumor of Panax notoginseng. If we could do more deeply research from cellular, molecular and genetic levels to explicit the multiple mechanism of anti-tumor, it will be greatly significant for treating tumor in clinic using Panax notoginseng.
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