异黄酮类化合物在不同氧化体系中的作用研究

摘要

The rancimat method, Hydrogen Peroxide-Inducement method and Xanthine-Xanthine Oxidase method were applied in our experiment to study the functional activies of Isoflavones. The vitro test indicated that Isoflavones had very strong bioactivities. The Daidzein,Genistein and their β -glycoside conjugates possessed different functional activities in different oxidation leaction systems,such as antioxidant reaction, antihemolysis reaction and free radidcal clearing away effect The reaction mechanism was also studied and proved that the corresponding relation ship existed between their structures and activities. We hope that these conclusions would be applieadle to the clinic research.%本文采用Rancimat法、过氧化氢诱导法、黄嘌呤-黄嘌呤氧化酶法研究了异黄酮类化合物在不同体系中对过氧化作用的抑制。研究发现不同异黄酮化合物在不同体系发挥不同作用，同其结构关系密切；并对作用机理进行讨论，提出异黄酮化合物作用的有效酚羟基的概念。