Polyphenols were extracted from longan seeds by using solvent extraction , ultrasound-assisted extraction and microwave-assisted extraction respectively. The content of polyphenols was detemined by the Folin-Ciocalteus method, and the extracted rates were calculated. The antioxidant activity of extracts were evaluated by total reducing power, superoxide anion radical and DPPH free radical scavenging activities. The extracted rates of polyphenol were (13.60 ±0.46) %, (9.85 ±0.76) %, (8.65 ±0.43) %, (12.04 ±1.69) %respectively. It was revealed that there were significant differences among these methods. The most radical scavenging activity against superoxide anion radical and DPPH free radical was microwave-assisted extract. In conclusion, the best result was obtained from microwave-assisted extraction. It was a linear relationship between concentrations and free radical scavenging abilities within a certain range.%采用溶剂萃取、超声辅助萃取和微波辅助萃取提取龙眼核中的多酚，比较萃取率以及其抗氧化活性的差异。分别采用溶剂萃取（回流法和浸提法）、超声辅助萃取和微波辅助萃取提取龙眼核中的多酚，采用Folin-Ciocalteus法测定多酚含量并计算提取率；测定并比较多酚的总抗氧化能力、对羟自由基和DPPH自由基的体外抗氧化能力。不同方法提取多酚含量差异明显，微波、回流、浸提和超声的提取率分别是（13.60±0.46）%、（9.85±0.76）%、（8.65±0.43）%、（12.04±1.69）%。不同方法提取的龙眼核多酚抗氧化活性各样差异，但总抗氧化能力大小差异不明显。龙眼核多酚对·OH清除能力依次为：IC50超声＜IC50微波展开▼
