2013年北京、成都、广州、上海四城市5－羟色胺3受体拮抗剂应用分析

摘要

目的：了解北京、成都、广州、上海四城市5－羟色胺3（5－HT3）受体拮抗剂的临床应用情况，为合理用药提供参考。方法：对《医院处方分析合作项目》组2013年北京、成都、广州、上海四城市5－HT3受体拮抗剂的处方数据进行分析，采用限定日剂量法计算用药频度、限定日费用。结果与结论：四城市5－HT3受体拮抗剂的销售金额和处方数均呈增长态势，使用品种均以昂丹司琼、托烷司琼为主，格拉司琼和帕洛诺司琼的使用在各地区间有较大差异。该类药物主要用于外科手术科室和肿瘤治疗相关科室。%OBJECTIVE:To analyze the clinical use of 5-HT3 receptor antagonists in Beijing, Chengdu, Guangzhou and Shanghai in order to provide reference for clinical rational use of 5-HT3 .METHODS:The prescriptions of 5-HT3 receptor antagonists in the four cities in 2013 collected from “Project of Prescription Analysis Cooperation”were analyzed with regard to DDDs and daily drug cost ( DDC ) using defined daily dose method.RESULTS &CONCLUSIONS:The consumption sum and the number of prescriptions of 5-HT3 receptor antagonists in all four cities witnessed an increase.Ondansetron and tropisetron were predominantly used in the above-mentioned four cities.But the use of gramsetron and palonosetron varied greatly among different regions.5-HT3 receptor antagonists were mainly use in surgical department and cancer treatment department.