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Novel sulfonamide compounds as serotonin receptor antagonists and serotonin transporter inhibitor
Novel sulfonamide compounds as serotonin receptor antagonists and serotonin transporter inhibitor
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机译:新型磺酰胺化合物作为5-羟色胺受体拮抗剂和5-羟色胺转运蛋白抑制剂
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摘要
The present invention relates to sulfonamide derivatives as a serotonin receptor antagonist and serotonin reuptake inhibitor and a pharmaceutically acceptable salt thereof. The sulfonamide derivatives have serotonin 5-HT2A and 5-HT2C receptor antagonizing and serotonin reuptake inhibiting functions, and thus may be efficiently applied to a CNS-related disease such as depression, obesity, psychosis, schizophrenia, suicidal tendency, anxiety, obsessional neurosis, migraine, appetite disorders, sleep disorders, stroke, and withdrawal symptoms caused by drug abuse.
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