多孔双相钙磷钛合金微弧氧化膜层的制备及生物相容性

摘要

为克服钛合金生物膜层单一相的缺陷,以Ti6A14V合金为基体,用微弧氧化法制得具有双相钙磷复合陶瓷膜层(BCP)的钛合金器件.通过控制工作液成分制得由不同比例的β-磷酸三钙(β-TCP)和羟基磷灰石(HA)组成的多孔性复合膜层.研究了电源占空比对BCP膜孔隙率和孔径大小的影响.采用能谱仪和X射线衍射仪分析了BCP膜层的组成与构相.通过模拟体液浸泡(SBF)和生物体植入试验,研究了BCP膜的生物相容性.结果表明,提高BCP膜层中的HA含量,有利于类骨物质的生成；而提高β-TCP含量,能使膜层中类骨物质的形成速率加快.当n(HA)(β-TCP)=6:4时,BCP膜的生物相容性最佳.%A porous biphasic calcium phosphate (BCP) coating was prepared on the surface of Ti6A14V alloy by microarc oxidation to overcome the defects of single-phase biofilm on titanium alloy. The porous composite coatings composed of different proportions of P-tricalcium phosphate (p-TCP) and hydroxyapatite (HA) were obtained by controlling the compositions of working electrolytes. The effect of duty cycle on the aperture and porosity of BCP coating was studied. The composition and structure of BCP was analyzed using energy spectrometer and X-ray diffractometer. The biocompatibility of BCP coating was studied by immersion in simulated body fluid (SBF) and implantation in organism. The results showed that the increase of HA content in BCP coating facilitates the formation of skeleton, while the increase of p-TCP speeds up the formation of bone materials. The biocompatibility of BCP coating is best when the molar ratio of HA to p-TCP is 6:4.