复方氨基酸注射液临床应用专家共识

摘要

复方氨基酸注射液是肠外营养中氮的来源,广泛应用于不能经胃肠道给予或经胃肠道给予不能满足其营养需求的患者,在营养治疗中起重要作用.但目前对于复方氨基酸注射液临床应用的指征、剂型、剂量、时机,国内并无系统的指南或共识.为了进一步规范复方氨基酸注射液的临床应用,中华医学会肠外肠内营养学分会(Chinese Society for Parenteral and Enteral Nutrition?CSPEN)及中国抗癌协会肿瘤营养专业委员会(Chinese Society of Nutritional Oncology?CSNO)组织全国专家,在系统性文献检索的基础上,参考美国肠外肠内营养学会(American Society for Parenteral and Enteral Nutrition?ASPEN)、欧洲临床营养和代谢学会(European Society for Clinical Nutrition and Metabolism?ESPEN)、CSPEN及CSNO指南,结合我国临床实践,经多次交流讨论,达成此共识.包括10条推荐意见,涉及不同患者的蛋白质需要量及氨基酸剂型选择.%Compound amino acid injection, as the source of nitrogen in parenteral nutrition, is administrated to patients with compromised gastrointestinal function or whose nutritional needs cannot be satisfied via the GI tract.Therefore, compound amino acid injection is crucial in nutrition therapies.However, a consensus does not exist in China regarding its indications, formulations, dosages, and the timing of administration.Experts in the field are recruited by the Chinese Society for Parenteral and Enteral Nutrition (CSPEN) and the Chinese Society of Nutritional Oncology ( CSNO) to formulate a consensus paper.The current paper aims to provide standardized guidance for clinical use of compound amino acid injection.The consensus paper is a composite of systematically reviewing pertinent literature, Chinese clinical practice, and multiple sessions of debate, discussion, and composition, with reference to guidelines from American Society for Parenteral and Enteral Nutrition ( ASPEN), European Society for Clinical Nutrition and Metabolism ( ESPEN), CSPEN, and CSNO.This consensus presents 10 recommendations for protein needs and appropriate compound amino acid injection formulas to serve varied patients.