目的：了解卫生部抗菌药物专项整治活动对某院急诊急性上呼吸道感染患者抗菌药物使用状况的影响。方法：回顾性分析2010年7月-2011年6月(整治前)和2011年7月-2012年6月(整治后)某院急诊急性上呼吸道感染全部病例在整治活动前后抗菌药物应用情况的差异。结果：整治后上呼吸道感染患者的每次抗菌药费用占总费用的比例由95.59%下降到78.99%；抗菌药物品种及类别结构得到优化和调整；不合理用药比例由20.25%下降到13.54%。结论：整治活动后抗菌药物应用指征的掌握有所改进；用药指标有所改进；抗菌药物使用剂量与用法不合理现象仍需改善。抗菌药物整治活动在该院取得了一定的效果，有效地促进了抗菌药物合理使用。%Objective: To investigate the effect of antibiotic in patients with acute upper respiratory tract infection in emergency department of the hospital, the special rectification activity was carried out by the Ministry of Health. Methods: This paper analyzed the differences of the application of antibiotic in patients with acute upper respiratory tract infection in emergency department of the hospital, from July 2010 to June 2011 retrospectively before and after the rectification activity. The intervention effect was analyzed and evaluated. Results: The proportion of per costs of antibiotic to total costs in patients with acute upper respiratory tract infection came down from 95.59% to 78.99% after the rectification activity. The product and the category of antimicrobial agent were improved. The rate of irrational antibiotic application came down from 20.25% to 13.54%. Conclusion: The management improves the application of antibiotic. The evaluative indicators of antibiotic have been improved. However, after the activity, the dosage and usage of antibiotic is still unreasonable. In the antibiotic rectification activity, the hospital has attained some achievements, promoted the rational utilization of antibiotic.
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