Objective To understand the characteristics of influenza B viruses circulation and serum antibody level in population in Ningbo from 2009 to 2010. Methods Samples were collected from the patients in sentinel hospitals for influenza virus isolation, and blood samples were taken from healthy people in July 2009 and March 2010 to detect influenza B viruses antibodies with magglutination-inhibition reaction. Results The circulation of influenza B virus Victoria lineage was active from 2009 to 2010,two circulation peaks were observed and new variant strains were detected since June. The serum antibody positive rate was 42. 12% for the samples taken from the healthy people in July 2009 and 51.11% for the samples taken in March 2010. Conclusion The circulation of influenza B virus Victoria lineage was related with the variation of its hemagglutinin gene and the antibody level to influenza B virus Victoria lineage increased obviously in population in Ningbo from 2009 to 2010.%目的 了解2009-2010年宁波市乙型流行性感冒(流感)病毒的流行特征及人群对乙型流感的抗体水平变化.方法 从流感监测哨点医院采集患者标本进行流感病毒分离及疫情监测,于2009年7月和2010年3月底2次采集宁波市正常人群血清,用微量血凝抑制法进行乙型流感抗体检测.结果 在2009-2010年期间乙型流感的Victoria系毒株比较活跃,共出现2次流行的高峰期,且从2009年6月起血凝素基因出现了新变异株.人群血清抗体水平检测结果,2009年7月采集的标本阳性率为42.12％,而2010年3月底采集的标本为51.11％.结论 2009-2010年Victoria系乙型流感的流行与毒株的血凝素基因变异有关.从2009年7月至2010年3月底,人群对Victoria系乙型流感的抗体阳性率有明显的增高.
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